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Authors
Ding, Yi
Fu, Yiru
Sun, Meng
Li, Yue
Li, Ang
Li, Ye
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Funding
Funding for this research was provided by:
the Shaanxi Natural Science Basic Research Program (Grant No. 2025JC-YBQN-1059)
the National Natural Science Foundation of China (Grant No. 82071078)
Key Project of Shaanxi Provincial Natural Science Foundation (2025 JC-QYXQ-045)
Key R&D Program of Shanxi Province (2025YF-04)
the Shaanxi Provincial High-level Talent Program and Young Talent Support Plan of Xi’an Jiaotong University
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Article History
Received: 27 May 2025
Accepted: 26 September 2025
First Online: 29 October 2025
Declarations
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: Human umbilical cord tissue was obtained at Renmin Hospital of Wuhan University under the project title of “Umbilical Cord Mesenchymal Stem Cell-Based Therapy for Venous Malformations in Mice” by the Clinical Research Ethics Committee of Renmin Hospital of Wuhan University (Ethics No. WDRY2022-K034, 25 February 2022). Written informed consent was obtained from the parents or legal guardians of all donors for the collection and use of umbilical cord samples. Human teeth were obtained at Xi’an Jiaotong University Affiliated Hospital of Stomatology under the project title of “Effect of Kaempferol in Treating Periodontitis-Related Bone Defects via EphrinB2” by the Medical Ethics Committee of the Stomatological Hospital, Xi’an Jiaotong University (Ethics No. 2023-XJKQIEC-KY-GXB-0008-002, 19 December 2023). Written informed consent was obtained from the parents or legal guardians of all donors. All the animal experiments were approved by the Biomedical Ethics Committee of Health Science Center of Xi’an Jiaotong University under the project title of “Mechanistic study on the regulation of stem cell-derived exosome secretion and function under microgravity conditions” (Ethics No. XJTUAE2014-2786, 27 December 2024).
: The authors declare no competing interests.
