Deng, Wei-juan
Tang, Rui
Ma, Meng-qing
Zhang, Hao
Cao, Chang-chun
Funding for this research was provided by:
Youth Science Foundation of Jiangxi Province (20212BAB216071)
Health Commission of Jiangxi Province (BKJP1220240788)
Jiujiang City Key Research and Development Program Project (2025_000694)
National Natural Science Foundation of China (82170698)
Article History
Received: 20 June 2025
Accepted: 13 October 2025
First Online: 14 November 2025
Declarations
:
: All animal experiments were conducted in accordance with the ARRIVE 2.0 guidelines and approved by the Animal Ethical and Welfare Committee of Nanjing Medical University (Title: Mechanistic Study of Adipose-derived Mesenchymal Stem Cells Promoting Repair after Acute Kidney Injury; Approval No.: IACUC-2001017; Date: March 4, 2022). This study strictly adhered to the Declaration of Helsinki, and adipose tissue collection was performed after obtaining written informed consent from the participants. The study protocol was approved by the Ethics Committee of Sir Run Run Shaw Hospital, Nanjing Medical University (Title: Protective Effects of Human Adipose-derived Mesenchymal Stem Cell-derived Extracellular Vesicles on Acute Kidney Injury in Mice; Approval No.: 2024-SR-007; Date: January 18, 2024). The THP-1 cell line (RRID: CVCL_0006) was obtained from Shanghai Zhongqiao Xinzou Biotechnology Co., Ltd. (originally purchased from ATCC, USA). For detailed information regarding compliance and prior ethical approval of the cell line, please visit the ATCC official website: .
: The authors declare no competing interests.