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Authors
Zhang, Yarui
Wang, Xueer
Chen, Qimei
Zhao, Shan
Bu, Lingwei
Wu, Shenhua
Huang, Jianyuan
Xu, Xunhong
Yang, Xinyu
Miao, Yong
Zhang, Lin
Zhang, Min
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Funding
Funding for this research was provided by:
the National Natural Science Foundation of China (82372538)
the National Natural Science Foundation of China (81402613)
the Natural Science Foundation of Guangdong Province (No. 2023A1515012827)
the GDMPA Key Laboratory Project of Scientific and Technological Innovation (No. 2023ZDZ12)
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Article History
Received: 17 July 2025
Accepted: 13 November 2025
First Online: 24 November 2025
Declarations
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: The clinical investigation was carried out in accordance with the principles of the Declaration of Helsinki. This study was approved by the Medical Ethics Committee of Nanfang Hospital of Southern Medical University. Signed informed consent was obtained from all participants (Protocol Title: A clinical study on the effects of a cell-free formulation derived from human umbilical cord mesenchymal stem cells on hair growth in patients with alopecia. Approval number: NFEC-2024-323; Approval Date: June 20, 2024). The original source of Human DPCs [ ] (WgainBio) has confirmed that there was initial ethical approval for collection of human cells, and that the donors had signed informed consent. The original source of HMCs [ ] (Shanghai Cell Bank) has confirmed that there was initial ethical approval for collection of human cells, and that the donors had signed informed consent.
: All animals used in this study were treated in accordance with the guidelines of the Experimental Animal Ethics Committee of Southern Medical University (Project Title: Mechanism research of the human umbilical cord–mesenchymal stem cell secretome on hair growth on hair growth; Approval number: SMU L202310002; approval Date: November 1, 2023Approval Date: November 1, 2023).
: Not applicable.
: The authors declare no competing interests.
