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Authors
Han, Runnan
Yu, Ning
Qi, GuoWei
Wang, Jing
Wu, Yanan
Qin, Chuan
Shi, Lin
Wang, Liang
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Funding
Funding for this research was provided by:
北京市自然科学基金资助项目 (7222185)
the Fund of Liaoning Provincial Education Department (JYTMS20230575)
National Natural Science Foundation of China (82072953)
the Top Young Talent Program of Liaoning Provincial Government (XLYC1907009)
Dalian Outstanding Young Talents Project (2021RJ12)
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Article History
Received: 2 July 2025
Accepted: 18 November 2025
First Online: 5 December 2025
Declarations
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: The mesenchymal stem cell-derived exosomes used in this study are sourced from a research project that has obtained ethical approval. The source project (title: Clinical Study on Umbilical Cord Mesenchymal Stem Cells in the Treatment of Acute Ischemic Stroke) was reviewed and approved by the Ethics Committee of the Stem Cell Clinical Research Institution, the First Affiliated Hospital of Dalian Medical University, with the approval number 2022-01 and the approval date of January 16, 2022. This study only involves the use of the aforementioned exosomes and does not involve human samples or human participation, thus there is no need to obtain written informed consent from patients or their guardians/legally authorized representatives.
: The animal study was approved by the Medical Ethics Committee of PLA General Hospital, with the project title “Research on Intelligent Recognition of Auditory Brainstem Evoked Potentials Based on Deep Learning” and approval date on March 2, 2021. The approval number is S2020-465-01. All procedures were conducted in accordance with relevant guidelines and regulations.
: The authors declare no competing interests.
