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Authors
Fang, Yuan
Chen, Yanni
Yu, Xinlang
Zhang, Jiakang
Zhu, Weina
Mou, Chenghong
Wang, Dawei
Chen, Ao
Zhang, Rui
Liu, Qizhi
Li, Taosheng
Jiang, Bin
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Funding
Funding for this research was provided by:
Jiangsu Provincial Department of Science and Technology (BK20241749)
Jiangsu Provincial Department of Science and Technology (BK20241749)
Jiangsu Association of Traditional Chinese Medicine (PDJH2024023)
Jiangsu Association of Traditional Chinese Medicine (PDJH2024023)
Nanjing Municipal Science and Technology Bureau (YKK21218)
Nanjing Municipal Science and Technology Bureau (YKK21218)
Nanjing Hospital of Chinese Medicine (YJJC202301)
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Article History
Received: 1 September 2025
Accepted: 18 November 2025
First Online: 28 November 2025
Declarations
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: This study was approved by the Ethics Committee of Southeast University on April 2, 2024 (Project title: Mechanistic study of ginsenoside Rg1 in promoting MSC-derived exosome secretion for the treatment of IBD via the IL-23/Th17–JAK/STAT3 signaling pathway ; Approval No. 20240402008). The work has been reported in accordance with the ARRIVE guidelines 2.0. Adipose-derived mesenchymal stromal cells (ADSCs, HUXMD-01001) were purchased from OriCell (Shanghai, China; ). OriCell has confirmed that the original collection of human tissues was conducted under institutional ethical approval and that informed consent was obtained from all donors prior to tissue procurement. The murine macrophage cell line RAW264.7 (CL-0190) was purchased from Procell (Wuhan, China). The human colonic epithelial cell line NCM460 (ZQ1079) was obtained from Zhong Qiao Xin Zhou Biotechnology Co., Ltd. (Shanghai, China; ). According to the provider, the establishment and distribution of this cell line were conducted in compliance with ethical standards, and informed consent was obtained from the original donors. All authors provided their consent for publication.
: The authors declare no competing interests.
