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Authors
Kanzawa, Takahiro https://orcid.org/0009-0004-7708-0384
Onoda, Atsuto
Okamoto, Azusa
Yue, Xu https://orcid.org/0009-0006-5062-9722
Shimode, Ryoko
Takamoto, Yukina
Suzuki, Sakiko https://orcid.org/0000-0003-2114-9499
Ueda, Kazuto https://orcid.org/0000-0003-3297-024X
Miura, Ryosuke
Suzuki, Toshihiko https://orcid.org/0000-0001-8760-1404
Tajiri, Naoki
Shimizu, Shinobu https://orcid.org/0000-0001-9066-3489
Morita, Saho
Yukawa, Hiroshi
Kohara, Hiroshi
Fukuda, Noritaka
Mitani, Yasuyuki
Hida, Hideki
Takahashi, Yoshiyuki
Sato, Yoshiaki https://orcid.org/0000-0001-6320-9176
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Funding
Funding for this research was provided by:
Japan Society for the Promotion of Science London (23K07428)
Japan Society for the Promotion of Science London (23K25192)
Japan Society for the Promotion of Science London (24K21339)
Japan Society for the Promotion of Science London (JPMXS0120330644)
SEI Group CSR Foundation (SEI Group CSR Foundation)
program for bridging the gap between R&D and the ideal society and generating economic and social value (program for bridging the gap between R&D and the ideal society and generating economic and social value)
Kidswell Bio Corporation (Kidswell Bio Corporation)
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Article History
Received: 5 February 2025
Accepted: 19 November 2025
First Online: 23 January 2026
Declarations
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: The experiments were conducted with the approval of the Animal Care and Use Committee of Nagoya University School of Medicine (Nagoya, Japan; permit Nos. M220140-002 and M220142-003) and in compliance with the Regulations on Animal Experiments at Nagoya University. The details of the approved project are as follows:
: Not applicable.
: T.K.,Y.S. and S.Sh. and have a collaborative research agreement supplying SHED free of charge for with Kidswell Bio Corporation. Y.M. is a board member of Kidswell Bio Corporation and has stock options of the company. T.K., S.Sh., H.Y., Y.M. and Y.S. have filed a patent for the application of SHED for the treatment and prevention of cerebral palsy. A.On., A.Ok., X.Y., R.S., Y.T., S.Su., K.U., R.M., T.S., N.T., S.M., H.K, N.F, H.H., and Y.T. declare no competing interests.
