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Authors
Zhang, Rui
Huang, Lei
Jin, Meng
Kou, Haiyang
Ma, Jie
Zhang, Weijie
Ma, Jianbing
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Funding
Funding for this research was provided by:
Natural Science Foundation of Shaanxi Province (2021JM-569)
Natural Science Foundation of Guizhou Province (Qiankehejichu-ZK [2024] yiban588)
Key Science and Technology of Shaanxi Province (2021SF-187)
Shaanxi Innovative Research Team for Key Science and Technology of China (2023⁃CX⁃TD⁃73)
Shaanxi Administration of Traditional Chinese Medicine (SZY-NLTL-2022-003)
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Article History
Received: 15 August 2025
Accepted: 20 November 2025
First Online: 30 November 2025
Declarations
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: Animal experiments in this study were approved by the Animal Care and Use Committee of Xi’an Jiaotong University (Approval title: The study on the functional mechanisms of aADSC-Exos regulating cartilage homestasis and articular microenviroment; Approval No. XJTUAE202103049; Date: 2021.03.05. Approval title: The function and molecular mechanisms of curcumin regulating FoxO3/Becn1 axis in ADSC to promote the derived exosomes to improve articular microenvironment and promote cartilage regeneration; Approval No. XJTUAE202202046༛Date: 2022.02.05), and the Animal Experimental Ethical Committee of Guiyang Healthcare Vocation University (Approval title: The molecular mechanism of curcumin alleviating ADSC senescence to improve the joint microenvironment and enhance OA therapeutic effect; Approval No. 2023-D-1; Date: 2023.06.19).
: All authors approved the manuscript for publication.
: The authors declare no competing interests.
