Jiang, Mingyue
Zhu, Yinhong
Zheng, Honghui
Chen, Huanjie
Luo, Weizhan
Deng, Zhencheng
Zhang, Hongbo
Su, Zhuquan
Li, Shiyue
Ma, Ning
Funding for this research was provided by:
Guangzhou Basic and Applied Basic Research Foundation (2023A04J1204)
Pearl River Talent Recruitment Program (2021QN02Y016)
Major Project of Guangzhou National Laboratory (GZNL2023A02006)
National Natural Science Foundation of China (82200355)
Article History
Received: 12 June 2025
Accepted: 13 January 2026
First Online: 2 February 2026
Declarations
:
: This study was conducted in accordance with the protocol approved by the Institutional Review Board of The First Affiliated Hospital of Guangzhou Medical University (Project Title: Construction and Application Evaluation of a Standardized Animal Model for COPD; Approval No.: ES-2024-085-01; Date of Approval: June 13, 2024). Written informed consent was obtained from all subjects prior to bronchoscopy. The human bronchial epithelial cells (HBECs, Lifeline, FC-0035) and human small airway epithelial cells (HSAECs, ATCC, PCS-301-010) used in this study were purchased from commercial vendors. According to the information provided by the respective manufacturers, ethical approval for donor tissue collection was obtained, and informed consent was secured from all donors. Relevant details can be found on the ATCC website ( ) and the Lifeline Cell Technology website ( ).
: Not applicable.
: The authors declare no competing interests.