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Authors
Xu, Na
Wang, Shihao
Yang, Tingting
Yu, Meiping
Sun, Yu
Zhan, Yongkun
Yu, Yongguo
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (No.82101950)
National Natural Science Foundation of China (No. 82572115 ,No.82271904 and 82070914)
Shanghai Natural Science Foundation of China (25ZR1402444)
National Key R&D Program of China (No.2022YFC2703400 and No. 2025YFC2700054)
Shanghai Municipal Commission of Economy and Informatization (No. 2025_GZL_RGZN_01036)
Cross Biomedical Engineering of Shanghai Jiao Tong University School of Medicine (No. 25X010301330)
Climb-B program of Shanghai Xinhua Hospital (No.XKPF2024B102)
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Article History
Received: 1 July 2025
Accepted: 11 March 2026
First Online: 18 March 2026
Declarations
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: All participants or their legal representatives granted informed consent to the pertinent physician for the utilization and dissemination of medical information and biological specimens. Distinct and explicit authorization was obtained for the release of each individual’s images. The genetic analysis and research were performed in accordance with established protocols approved by the local institutional review boards. This study, approved On February 19, 2021, demonstrates its adherence to the ethical standards and regulations of the Ethics Committee of Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University(XHEC-NSFC-2021-025). Ethical Approval Title: Research on the Mechanism of OTUD5 Mutation Impacting Neuronal Development in Intellectual Disabilities Approval Date: February 19, 2021.
: Not applicable.
: The authors declare no competing interests.
: All participants or their legal representatives granted informed consent to the pertinent physician for the utilization and dissemination of medical information and biological specimens. Distinct and explicit authorization was obtained for the release of each individual’s images.
