Sun, Yi
Yu, Juan
Shi, Yang
Wang, Yang
Duan, Xingxiang
Xie, Menghan
Ouyang, Qi
Zhao, Yan
Wang, Mei
Zhou, Baicun
Xu, Caiyun
Lu, Guangxiu
Lin, Ge
Funding for this research was provided by:
Fund of National Engineering and Research Center of Human Stem Cell (2019RES01)
Key Research and Development Program of Hunan Province (2023SK2069)
Natural Science Foundation of Changsha (kq2208260)
Hunan Provincial Natural Science Foundation of China (2025JJ90231)
Health Research Project of Hunan Provincial Health Commission (W20242015)
Article History
Received: 12 October 2025
Accepted: 13 March 2026
First Online: 23 March 2026
Declarations
:
: For the derivation and research use of clinical-grade hESCs, the project titled “Establishment of a Clinical Human Embryonic Stem Cell Bank” were approved by the Ethics Committee of CITIC-Xiangya Reproductive & Genetic Hospital (Approval date: April 10, 2017, No. LL-SC-2017-003). Written informed consent was obtained from all donors prior to this study. Animal study titled “Efficacy of Using Hepatocyte-Like Cells Derived from Induced Differentiation of Human Embryonic Stem Cells in Treating Liver Diseases” was approved by the Institutional Animal Care and Use Committee (IACUC) of Central South University (Approval date: January 25, 2022, No. CSU-2022-01-0035).
: Not applicable.
: The authors declare no competing interests.