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Authors
Chen, Qi
Chen, Xiaolong
Yang, Qu
Miao, Xinxin
Yuan, Jinghong
Ding, Shuihua
Ding, Rui
Cai, Shenghao
Li, Bin
Cheng, Xigao
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (82460439)
National Natural Science Foundation of China (82572834)
Science and Technology Research Project of the Jiangxi Provincial Department of Education (GJJ210128)
Medical-Engineering Interdisciplinary Talent Development Program of Jiangxi Medical College, Nanchang University (28740109)
Interdisciplinary Innovation Fund of Nanchang University (PYJX20230005)
Jiangxi Provincial Key Laboratory of Spine and Spinal Cord Disease (2024SSY06131)
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Article History
Received: 31 December 2025
Accepted: 13 April 2026
First Online: 20 April 2026
Declarations
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: Human nucleus pulposus specimens were obtained with written informed consent from all participants. The study procedures involving human materials were approved by the Biomedical Research Ethics Committee of the Second Affiliated Hospital of Nanchang University under the approved project entitled “Construction of a Precision Diagnostic and Therapeutic System for Complex Lumbar Spine Diseases” (Approval No. I-BREC2023-6, Date of Approval: January 12, 2023). All animal experiments were approved by the Animal Ethics Committee of Nanchang University under the project entitled “Study of the Effect and Mechanism of Biologics A in the Treatment of Intervertebral Disc Degeneration” (Approval No. NCULAE-20221031077, Date of Approval: October 31, 2022), and were conducted in accordance with institutional guidelines for the care and use of laboratory animals.
: All the authors approved the publication.
: The authors declare no competing interests.
