Lee, Khang Leng https://orcid.org/0000-0003-0576-7377
Wee, Hannah Su-Ann https://orcid.org/0009-0001-6806-6343
Teng, Zi Yi
Tay, Hui Min
Chee, Ying Jie
Tan, Eunice Xiang Xuan
Dan, Yock Young
Muthiah, Mark D.
Dalan, Rinkoo
Hou, Han Wei
Cheung, Christine https://orcid.org/0000-0001-7127-9107
Funding for this research was provided by:
National Medical Research Council
National Research Foundation Singapore
Ministry of Education - Singapore
Lee Kong Chian School of Medicine, Nanyang Technological University (Vascular Research Initiative)
Article History
Received: 17 January 2026
Accepted: 18 June 2026
First Online: 25 June 2026
<b>Declarations</b>
Ethics approval and consent to participate: The project “Effects of Dapagliflozin and Metformin on Vascular Function in Newly Diagnosed Treatment-Naïve Type 2 Diabetes – A Randomized Controlled Trial (DMVascular Study)” was performed at Tan Tock Seng Hospital in Singapore and was approved by the National Healthcare Group Ethics Board (DSRB reference: 2018 − 00899) on March 10, 2023.
Competing interests: M.D.M has served as a consultant to Roche, Astellas and Gilead, Perspectum, and Echosens. He also serves as the CMO of LiverGENIX PTE LTD. All the other authors declare no competing interests.