Berglund, Agnethe https://orcid.org/0000-0001-9185-1342
Johannsen, Emma B. https://orcid.org/0000-0002-1017-7702
Skakkebæk, Anne https://orcid.org/0000-0001-9178-4901
Chang, Simon https://orcid.org/0000-0003-1130-3659
Rohayem, Julia https://orcid.org/0000-0002-7790-6631
Laurentino, Sandra https://orcid.org/0000-0002-5213-2756
Hørlyck, Arne https://orcid.org/0000-0003-4624-6973
Drue, Simon O. https://orcid.org/0000-0002-1401-6527
Bak, Ebbe Norskov https://orcid.org/0009-0003-6033-8521
Fedder, Jens https://orcid.org/0000-0001-5383-5501
Tüttelmann, Frank https://orcid.org/0000-0003-2745-9965
Gromoll, Jörg https://orcid.org/0000-0002-7788-8138
Just, Jesper https://orcid.org/0000-0002-3825-0000
Gravholt, Claus H. https://orcid.org/0000-0001-5924-1720
Funding for this research was provided by:
Danmarks Frie Forskningsfond (2096-00165A)
Aarhus Universitet
Familien Hede Nielsens Fond
A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal
Novo Nordisk Fonden (NNF15OC0016474)
Article History
Received: 17 April 2024
Accepted: 24 September 2024
First Online: 8 October 2024
Declarations
:
: Informed written consent was obtained for all participants and all clinical investigations were conducted according to the principles expressed in the Declaration of Helsinki. The study was notified to the Danish Data Protection Agency and to the Legal Department of Central Denmark Region (1-16-02-51-18) and approved by the ethical committee of Central Denmark Region (1-10-72-25-18). The data on Klinefelter syndrome was approved by The Danish Data Protection Agency and the local ethics committee (Region Midtjylland, Denmark number M-20080238). This research has been registered at ClinicalTrials.gov (Clinical trial NCT00999310). The data on 46,XX female controls stems from a study on Turner syndrome that has been approved by the ethical committee of Central Denmark Region (reference number M20110235).
: Not applicable.
: The authors declare no competing interests.