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Article History

Received: 2 February 2026

Accepted: 23 March 2026

First Online: 5 April 2026

Declarations

:

: All human studies were conducted in accordance with applicable ethical regulations and were approved by the Ethics Committee of the Medical Association of Hamburg (Ethik-Kommission der Ärztekammer Hamburg; approval number PV5252). Informed consent was obtained from all participants. All murine experiments were approved by the responsible federal health authorities of the State of Hamburg (approvals A008/2020, N041/2020, and N001/2025 for in vivo experiments; T-008 and T-011 for organ removal) and were performed in accordance with institutional guidelines and local legislation.

: Not applicable.

: The authors declare no competing interests.