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Article History

Received: 3 June 2019

Accepted: 28 August 2019

First Online: 15 October 2019

Ethics approval and consent to participate

: The study was approved by the Local Ethics Committee - Humanitas Clinical and Research Center IRCCS (authorization 2/18, 17/04/2018). A specific informed consent was not required according to the Local Ethics Committee rules for retrospective and observational study design (the patient management was not influenced or changed).

: Not applicable. All images and data were anonymous.

: A. Chiti received speaker honoraria from General Electric and Sirtex Medical System, acted as scientific advisor to Blue Earth Diagnostics and Advanced Accelerator Applications, and benefited from an unconditional grant from Sanofi to Humanitas University. All honoraria are outside the scope of the submitted work. M. Kirienko is supported by an AIRC (Italian Association for Cancer Research) scholarship funded by a grant won by A.C. (IG-2016-18585). A. Lania received speaker honoraria from IBSA, Pfizer, and IPSEN. All honoraria are outside the scope of the submitted work. P.A. Erba received speaker honoraria from General Electric, acted as scientific advisor to Gamma Servizi, and benefited from grant from Advanced Accelerator Applications and a research contract from Sigma Tau/Alfasigma. All honoraria are outside the scope of the submitted work. All other authors declare that they have no competing interests.