Aliaga, Antonio https://orcid.org/0009-0006-9792-7815
Therriault, Joseph https://orcid.org/0000-0002-7826-4781
Quispialaya, Kely https://orcid.org/0009-0000-6982-7143
Aliaga, Arturo https://orcid.org/0000-0001-6627-2939
Kunach, Peter https://orcid.org/0000-0001-7428-6812
Macedo, Arthur C. https://orcid.org/0000-0002-3957-0284
Hopewell, Robert https://orcid.org/0000-0002-2478-5872
Rahmouni, Nesrine https://orcid.org/0009-0004-3081-8468
Soucy, Jean-Paul https://orcid.org/0000-0002-8422-2326
Massarweh, Gassan https://orcid.org/0000-0003-2259-9627
Guiot, Marie-Christine
Chan, Tevy https://orcid.org/0009-0001-9134-5949
Klostranec, Jesse https://orcid.org/0000-0003-3553-0530
Abreu Diaz, Aida Mary https://orcid.org/0000-0002-6301-3496
Rocha, Andreia https://orcid.org/0000-0003-1567-3374
Carello-Collar, Giovanna https://orcid.org/0000-0003-4644-0151
Machado, Luiza S. https://orcid.org/0000-0001-8387-3832
De Bastiani, Marco Antônio https://orcid.org/0000-0003-3924-5278
Guerini de Souza, Débora https://orcid.org/0000-0003-2982-4989
Souza, Diogo O. https://orcid.org/0000-0002-4322-0404
Zimmer, Aline R. https://orcid.org/0000-0002-8309-7068
Gauthier, Serge https://orcid.org/0000-0003-4272-3330
Pascoal, Tharick A. https://orcid.org/0000-0001-9057-8014
Zimmer, Eduardo R. https://orcid.org/0000-0002-5349-0053
Rosa-Neto, Pedro https://orcid.org/0000-0001-9116-1376
Funding for this research was provided by:
Consortium canadien en neurodégénérescence associée au vieillissement (MOP-11-51-31 -team 1)
Fonds de Recherche du Québec - Santé (Chercheur Boursier, 2020-VICO-279314)
Canadian Institutes of Health Research (MOP-11-51-31; RFN 152985, 159815, 162303)
Alzheimer's Association (NIRG-12-92090, NIRP-12-259245)
Fondation Brain Canada (CFI Project 34874, 33397)
Article History
Received: 19 November 2024
Accepted: 2 March 2025
First Online: 1 April 2025
Declarations
:
: The studies involving human participants were reviewed and approved by both the Douglas-Bell Canada Brain Bank's ethics board and the Douglas Research Centre affiliated with McGill University scientific review committee. According to institutional procedures for autopsy consents for post-mortem tissue, the patients/participants provided their consent to participate in this study with their written information.
: According to institutional procedures for autopsy consents for post-mortem tissue, the patients/participants provided informed consent for publication of the study.
: JT has received consultancy fees from the Neurotorium educational platform and from Alzheon Inc, outside the scope of the present work. PR-N has served at scientific advisory boards and/or as a consultant for Roche, Novo Nordisk, Eisai, and Cerveau radiopharmaceuticals. ERZ has served on the scientific advisory board of Nintx, Novo Nordisk and Masima. He is also a co-founder and a minority shareholder at Masima. All other authors report no disclosures.