Nielsen, Andreas Wiggers https://orcid.org/0000-0001-8180-6871
van Praagh, Gijs D.
van der Geest, Kornelis S. M.
Hansen, Ib Tønder
Nielsen, Berit Dalsgaard
Kjær, Søren Geill
Blegvad-Nissen, Jesper
Rewers, Kate
Sørensen, Christian Møller
Brouwer, Elisabeth
Hauge, Ellen-Margrethe
Gormsen, Lars Christian
Slart, Riemer H. J. A.
Keller, Kresten Krarup
Funding for this research was provided by:
Health Research Fund of Central Denmark Region
Aarhus Universitetshospital
Gigtforeningen
Frimodt-Heineke Fonden
Aase og Ejnar Danielsens Fond
A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal
Regional Hospital Central Jutland Research Foundation
Article History
Received: 8 December 2024
Accepted: 28 March 2025
First Online: 30 April 2025
Declarations
:
: This study complies with the Declaration of Helsinki. The study protocol for the Danish cohort was approved by the Regional Scientific Ethical Committee for the Central Denmark Region (reference number 1-10-72-99-19) and the Internal List of Research Projects in Central Denmark Region—former Danish Data Protection Agency (reference number: 1-16-02-166-19). All patients provided written informed consent. The study protocol for the Dutch cohort was approved by the ethics committee of the University Medical Center Groningen (METc 2020/220).
: Informed written consent was obtained from all individual participants included in the Danish cohort, including the patients depicted in Fig. . Informed consent was not required for the Dutch cohort due to the retrospective design of the study.
: AWN, GP, ITH, SGK, JB-N, CMS, KR, LCG, EB and KK have nothing to declare. BDN has received speaking fees unrelated to this manuscript from Novartis and AbbVie. EMH has received grants unrelated to this manuscript from Novo Nordic Foundation, Roche, Novartis and personal fees from AbbVie, Sanofi, SOBI, Merck Sharp & Dohme and Union Chimique Belge. KG reports speaking fee from Roche and research support from AbbVie and Siemens paid to the UMCG, outside the submitted work. RS received unrestricted research grants from Siemens Healthineers and Pfizer. Furthermore, RS serves as an editor for EJNMMI.