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Authors
Tanegashima, Tokiyoshi
Shiota, Masaki https://orcid.org/0000-0002-3306-4858
Doi, Atsushi
Tatarano, Shuichi
Kamba, Tomomi
Igawa, Tsukasa
Masumori, Naoya
Uemura, Hirotsugu
Kamoto, Toshiyuki
Higashijima, Katsuyoshi
Mitsunari, Kensuke
Uemura, Hiroji
Sumiyoshi, Takayuki
Isoda, Takuro
Ishigami, Kousei
Tokunaga, Shoji
Eto, Masatoshi
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Funding
Funding for this research was provided by:
Bayer Yakuhin (Bayer Yakuhin)
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Article History
Received: 10 March 2026
Accepted: 27 May 2026
First Online: 2 June 2026
Declarations
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: The protocol was approved by the ethics review committee of each participating institution. All participants provided written informed consent. This study does not involve any animal experiments.Informed consent was obtained from all individual participants included in the study.
: The authors affirm that human research participants provided informed consent for publication.
: Masaki Shiota received honoraria from Janssen Pharmaceutical, AstraZeneca, Astellas Pharma, Sanofi, and Bayer and research funding support from Daiichi Sankyo. Tomomi Kamba received honoraria from MSD and Takeda Pharmaceutical. Masatoshi Eto received honoraria from Takeda Pharmaceutical, Janssen Pharmaceutical, AstraZeneca, and Astellas Pharma and research funding support from Astellas Pharma, Sanofi, and Takeda Pharmaceutical.
: This study was registered on the University Hospital Medical Information Network (UMIN) in Japan on May 11, 2020 (protocol ID: UMIN000040358).
