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MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis

Crossref DOI link: https://doi.org/10.1186/s13567-025-01459-2

Published Online: 2025-02-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Bai, Huifang

Dang, Qianqian

Chen, Guoliang

Xie, Lingfeng

Wang, Saining

Jiang, Ning

Wu, Xiaoxia

Zhang, Shuyan

Wang, Xuelin https://orcid.org/0000-0001-7303-8534
Funding

Funding for this research was provided by:

Jilin Province Key Research and Development Program of China (20230202086NC)
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Article History

Received: 20 August 2024

Accepted: 30 September 2024

First Online: 4 February 2025

Declarations

:

: All mice were raised and handled strictly following the National Institutes of Health guide for the care and use of laboratory animals and approved by the Ethics Committee for Animal Experiments of Jilin University (NO. 202201-104, date: 25/2/2022).

: The authors declare that they have no competing interests.

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