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Contribution of critical amino acid residues in the RNA-dependent RNA polymerase to the replication fidelity and viral ribavirin sensitivity of porcine reproductive and respiratory syndrome virus

Crossref DOI link: https://doi.org/10.1186/s13567-025-01517-9

Published Online: 2025-04-19

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhang, Xiaoyan

Yang, Ziyin

Zhang, Zhibang

Wang, Zhisheng

Zhao, Yipeng

Yang, Taotao

Gong, Jinxiang

Feng, Kang

He, Junping

Zheng, Qisheng

Hou, Jibo

Li, Pengcheng https://orcid.org/0000-0003-1643-7701
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (31960697, 32260880)

Double Thousand Plan of Jiangxi Province (jxsq2019101056)
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Text and Data Mining valid from 2025-04-19

Version of Record valid from 2025-04-19
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Article History

Received: 14 November 2024

Accepted: 10 February 2025

First Online: 19 April 2025

Declarations

:

: The Animal Care and Ethics Committee of Yichun University (Permit No. JXSTUDKY2024006) approved the animal study. All animal experiments were conducted per the local legislation and institutional requirements. Written informed consent was obtained from the owners for the participation of their animals in this study.

: The authors declare that they have no competing interests.

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