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Relevance of porcine intestinal organoids as a surrogate for animal experimentation: application to the investigation of host–virus interactions during porcine coronavirus infection

Crossref DOI link: https://doi.org/10.1186/s13567-025-01657-y

Published Online: 2025-11-21

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Percevault, Ludivine https://orcid.org/0009-0008-9441-9035
Tranchevent, Léon-Charles https://orcid.org/0000-0002-1257-4824
Bigault, Lionel https://orcid.org/0000-0001-5545-6089
Berthaud, Maxime https://orcid.org/0009-0009-1688-6858
Le Gloahec, Damien https://orcid.org/0009-0006-9118-3392
Lucas, Pierrick https://orcid.org/0000-0002-2844-6157
Carnet, Flora https://orcid.org/0000-0002-7711-0369
Le Roux, Aurélie https://orcid.org/0009-0008-0786-748X
Le Diguerher, Gérald

Paboeuf, Frédéric

Dory, Daniel https://orcid.org/0000-0003-0138-7713
Blanchard, Yannick https://orcid.org/0000-0002-4711-6671
Grasland, Béatrice https://orcid.org/0000-0001-5777-673X
Contrant, Maud https://orcid.org/0009-0006-5849-4850
Funding

Funding for this research was provided by:

Région Bretagne (0311 /21005503/00000433)

Département des Côtes d'Armor

Saint-Brieuc Armor Agglomération (340-2021)

Institut Carnot AgriFood transition (2024_00072)

Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
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Text and Data Mining valid from 2025-11-21

Version of Record valid from 2025-11-21
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Article History

Received: 16 May 2025

Accepted: 12 August 2025

First Online: 21 November 2025

Declarations

:

: This animal study was reviewed by the ethics committee and approved by the French Ministry of Higher Education and Research (authorization number: #39769–2022120716251321).

: The authors declare that they have no competing interests.

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