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Histone deacetylase 3 facilitates TNFα-mediated NF-κB activation through suppressing CTSB induced RIP1 degradation and is required for host defense against bacterial infection

Crossref DOI link: https://doi.org/10.1186/s13578-022-00814-6

Published Online: 2022-06-03

Published Print: 2022-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yang, Liping

Chen, Shengchuan

Xia, Jingyan

Zhou, Ying

Peng, Linan

Fan, Huimin

Han, Yu

Duan, Lihua

Cheng, Genhong

Yang, Heng http://orcid.org/0000-0002-6713-2783
Xu, Feng
Funding

Funding for this research was provided by:

Chinese Academy of Medical Sciences (2021-1-I2M-047, 2016-I2M-1-005, 2020-PT310-006, 2019XK310002, 2018TX31001)

Chinese Academy of Meteorological Sciences (3332018131)

National Natural Science Foundation of China (82073181, 81802870, 2017YFA0506200, 82070006, 81770008)

Jiangsu province (BK20211554, BK20170407)

the innovative and entrepreneurial team grant fromJiangsu province (2018-2021)
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Text and Data Mining valid from 2022-06-03

Version of Record valid from 2022-06-03
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Article History

Received: 25 December 2021

Accepted: 11 May 2022

First Online: 3 June 2022

Declarations

:

: All animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of Suzhou Institute of Systems Medicine (ISM-IACUC-0019-R) in accordance with the guidelines for the ethical treatments of animals.

: Yes.

: The authors declare that they have no competing interests.

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