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Article History

Received: 28 March 2022

Accepted: 22 July 2022

First Online: 8 August 2022

Declarations

:

: The authors have no conflicts to disclose.

: All experimental and research procedures were in accordance with relevant regulations. All patients diagnosed pathologically with gastric cancer (GC) at the Chang Gung Memorial Hospital (CGMH) from 2000 to 2005 were enlisted after informed consent. None of the patients had received radiotherapy and chemotherapy before surgery and all were undergone gastric resection. All the pathologic analyses and biological examination were conducted with informed consent. The research protocol was approved and verified by the Medical Ethics and Human Clinical Trial Committee of the Chang Gung Memorial Hospital (IRB NO. 201702000B0C101). The patients were followed regularly at the outpatient department in the Chang Gung Memorial Hospital every 3 months in the first 2 years, every 6 months between 3 to 5 years, and once a year thereafter. All animal experiments were performed in accordance with the Guide for Care and Use of Laboratory Animals issued by the Institutional Animal Care and Use Committee of Chang Gung University and the National Institutes of Health of United States (CGU106-142).

: Not applicable.

: The authors declare that they have no conflict of interest.