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Article History

Received: 1 March 2020

Accepted: 25 August 2020

First Online: 9 December 2020

Ethics approval and consent to participate

: The Allergy Diary is CE1 registered. By using k-anonymity, the data were all anonymized including the data related to geolocalization. MASK-air^® is in line with the General Data Protection Regulation (GDPR) EU Directive 95/46/EC. Independent Review Board approval was not required since the study is observational and users agree to having their data analysed (terms of use).

: Not applicable.

: Dr. Almeida reports grants from ERDF (European Regional Development Fund) through the operation POCI-01-0145-FEDER-029130 (“mINSPIRERS—mHealth para medição e melhoria da adesão à medicação nas doenças respiratórias obstrutivas crónicas—generalização e avaliação de tecnologias de gamificação, suporte por pares e processamento avançado de imagem”) funded by the Programa Operacional Competitividade e Internacionalização—COMPETE2020 and by National Funds through FCT (Fundação para a Ciência e a Tecnologia, during the conduct of the study.Dr. Ansotegui reports personal fees from Hikma, Roxall, Astra Zeneca, Menarini, UCB, Faes Farma, Sanofi, Mundipharma, outside the submitted work.Bachert: Meda, Stallergenes and ALK (speaker). J Bousquet reports personal fees and other from Chiesi, Cipla, Hikma, Menarini, Mundipharma, Mylan, Novartis, Sanofi-Aventis, Takeda, Teva, Uriach, outside the submitted work. other from Kyomed. Dr. Bosnic-Anticevich reports personal fees from Teva, Boehringer Ingelheim, Sanofi, GSK, AstraZeneca, outside the submitted work. Dr. Cardona reports personal fees from ALK, Allergopharma, Allergy Therapeutics, Diater, LETI, Thermofisher, Stallergenes, outside the submitted work. Dr. Cecchi reports personal fees from Menarini, Malesci, ALK Abellò, Menarini, non-financial support from Mundipharma, outside the submitted work.Dr. Correia-de-Sousa reports other from Boheringer Ingelheim, GSK, AstraZeneca, outside the submitted work. Dr. Cruz reports grants and personal fees from Astrazeneca, grants from GSK, personal fees from Boehringer Ingelheim, CHIESI, NOVARTIS, Eurofarma, MEDA Pharma, Boston Scientific, outside the submitted work. Dr. Devillier reports personal fees and non-financial support from Astra Zeneca, Mylan, Stallergenes Greer, personal fees from ALK Abello, Menarini, GlaxoSmithKline, Sanofi, outside the submitted work. Dr. Haahtela reports personal fees from Mundipharma, Novartis, and Orion Pharma, outside the submitted work. Dr. Eller reports other from Thermofisher Scientific, outside the submitted work. Dr. Fonseca reports personal fees from AstraZeneca, GSK, Novartis, Teva, grants from Mundipharma, outside the submitted work. Dr. Ivancevich reports personal fees from Faes Farma Euro-Farma Argentina, other from Lboratorios Casasco, Sanofi, outside the submitted work. Dr. Fokkens reports grants from Mylan, ALK, Allergy Therapeutics, GSK, Sanofi, Novartis, outside the submitted work. Dr. Klimek reports personal fees from MEDA, Sweden, Boehringer Ingelheim, Germany, grants and personal fees from ALK Abelló, Denmark, Novartis, Switzerland, Allergopharma, Germany, Bionorica, Germany, GSK, Great Britain, Lofarma, Italy, grants from Biomay, Austria, HAL, Netherlands, LETI, Spain, Roxall, Germany Bencard, Great Britain, outside the submitted work. Dr. Kuna reports personal fees from Adamed, Boehringer Ingelheim, AstraZeneca, Chiesi, FAES, Berlin Chemie, Novartis, Polpharma, Allergopharma,outside the submitted work. Dr Kvedariene has received payment for consultancy from GSK and for lectures from StallergensGreer, Berlin-CHemie outside the submitted work. Dr. Larenas Linnemann reports personal fees from Amstrong, Astrazeneca, Boehringer Ingelheim, Chiesi, DBV Technologies, Grunenthal, GSK, MEDA, Menarini, MSD, Novartis, Pfizer, Sanofi, Siegfried, UCB, grants from Sanofi, Astrazeneca, Novartis, UCB, GSK, TEVA, Boehringer Ingelheim, Chiesi, outside the submitted work. Dr. Melén reports personal fees from Advisory board reimbursement from Novartis, outside the submitted work. Dr. Ralph Mösges reports personal fees from ALK, allergopharma, Allergy Therapeutics, Hexal, personal fees from Servier, personal fees from Klosterfrau, Stada, UCB, Friulchem, grants from ASIT biotech, Nuvo, Bayer, FAES, GSK, MSD, Johnson&Johnson, Meda, Optima, Ursapharm, BitopAG, Hulka, grants and personal fees from Bencard, grants from Leti, Stallergenes, grants, personal fees and non-financial support from Lofarma, non-financial support from Roxall, from Atmos, from Bionorica, Otonomy, Ferrero, personal fees and non-financial support from Novartis, outside the submitted work. Dr. Papadopoulos reports grants from Gerolymatos, personal fees from Hal Allergy B.V., Novartis Pharma AG, Menarini, Hal Allergy B.V., Mylan, outside the submitted work. Dr. Pfaar reports grants and personal fees from ALK-Abelló, Allergopharma, Stallergenes Greer, HAL Allergy Holding B.V./HAL Allergie GmbH, Bencard Allergie GmbH/Allergy Therapeutics, Lofarma, ASIT Biotech Tools S.A., Laboratorios LETI/LETI Pharma, Anergis S.A., grants from Glaxo Smith Kline, Biomay, Nuvo, Circassia, personal fees from MEDA Pharma/MYLAN, Mobile Chamber Experts (a GA²LEN Partner Indoor Biotechnologies, Astellas Pharma Global, outside the submitted work. Dr. Ryan reports personal fees from Mylan, AZ, AZ, GSK, from Chiesi, BI, grants from Mylan, outside the submitted work.Dr Schmid-Grendelmeier reports honarium and consultancy fees from ALK-Abello, Allergopharma, Bencard, MEDA and Stallergenes Dr. Stelmach reports grants from São Paulo Research Foundation, MSD, grants and personal fees from Novartis, grants, personal fees and non-financial support from AstraZeneca, Chiesi, personal fees and non-financial support from Boheringer Ingelheim, outside the submitted work. Dr. Todo-Bom reports grants and personal fees from Novartis, Mundipharma, GSK Teva Pharma, personal fees from AstraZeneca, grants from Boehringer Ingelheim, Sanofi, Leti, outside the submitted work. Dr. Toppila-Salmi reports other from Biomedical Systems Ltd., Roche Ltd., grants from Erkko Foundation, outside the submitted work. Dr. Waserman reports other from CSL Behring Shire, AstraZeneca, Teva, Meda, other from Merck, GSK, Novartis, Pediapharm, Aralez Sanofi, Stallergenes, outside the submitted work.