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Article History

Received: 30 July 2020

Accepted: 8 October 2020

First Online: 23 October 2020

Ethics approval and consent to participate

: The study was approved by the Ethics Committee for Clinical Research of the Hospital Clínic de Barcelona. All patients signed informed consent to participate.

: All participants signed their written consent for publication.

: MCS-H reports grants from MYLAN during the conduct of the study. Outside this study, she reports personal fees from MYLAN, Sanofi, Novartis, and Merck. AMN reports grants from MYLAN during the conduct of the study. Outside this study, she reports personal fees from GSK, AstraZeneca, Merck, and MYLAN. CC reports having served as a consultant to Mylan and AstraZeneca; having been paid lecture fees by AstraZeneca, GSK, Mylan, and MSD; and grants from Roxall, Novartis, AstraZeneca, and Sanofi. AdC reports grants from MYLAN during the conduct of the study. Outside this study, he reports grants and personal fees from MYLAN, FAES Pharma, Novartis, Allakos, and Sanofi; and personal fees from ALK, GSK, and MSD. JS reports grants from MEDA during the conduct of the study; grants and personal fees from SANOFI; and personal fees from GSK, NOVARTIS, ASTRA ZENECA, MUNDIPHARMA, and FAES FARMA, outside the submitted work. JM reports personal fees and other from SANOFI-GENZYME & REGENERON, NOVARTIS; grants and personal fees from MYLAN-MEDA Pharma and URIACH Group; and personal fees from Mitsubishi-Tanabe, Menarini, UCB, AstraZeneca, GSK, and MSD, outside the submitted work. AV reports grants from MEDA during the conduct of the study.