Gao, Chao https://orcid.org/0000-0002-6933-1727
Lu, Xinxing
Jiang, Yiwei
Tang, Ying
Ni, Yunhui
Chen, Hanbing
Wu, Xiaojing
Zhou, Xing
Yang, Yi
Liu, Ling
Chao, Jie
Xie, Jianfeng
Qiu, Haibo
Funding for this research was provided by:
The Special Funds of the National Natural Science Foundation of China (82341032)
The Key Program of the National Natural Science Foundation of China (81930058)
Jiangsu Provincial Key Research and Development Program (BE2019749)
Jiangsu Provincial Key Laboratory of Critical Care Medicine (BM2020004)
The National Science and Technology Major Project of China (2023ZD0506500)
The Natural Science Foundation of Jiangsu Province (BK20240210)
Article History
Received: 23 January 2025
Accepted: 8 October 2025
First Online: 27 October 2025
Declarations
:
: Human research: The prospective clinical cohort was approved by the Ethics Committee of Zhongda Hospital, Southeast University, China (Approval No. 2022ZDSYLL196-P01). Written informed consent was obtained from all participants or their legally authorized representatives. The study complied with the Declaration of Helsinki. Animal research: All animal procedures were approved by the Institutional Animal Care and Use Committee of the Medical School of Southeast University (Permit No. 20190222014) and adhered to the NIH Guidelines for the Care and Use of Laboratory Animals.
: Not applicable. This manuscript does not contain any individual person’s data in any form (including individual details, images, or videos).
: The authors declare that there are no conflicts of interest regarding the publication of this article. All authors have no financial or non-financial competing interests to disclose.