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The deubiquitinase OTUD3 stabilizes IRP2 expression to reduce hippocampal neuron ferroptosis via the p53/PTGS2 pathway to ameliorate cerebral ischemia–reperfusion injury

Crossref DOI link: https://doi.org/10.1186/s40001-024-02095-w

Published Online: 2024-10-17

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Hou, Dan

Hu, Yujie

Yun, Tian

Li, Hongxin

Yang, Guoshuai

Yu, Dan
Funding

Funding for this research was provided by:

Hainan Province Science and Technology Special Fund (ZDYF2023SHFZ105)

Hainan Provincial Natural Science Foundation of China (2019RC386)

Hainan Province Clinical Medical Center (0202067)

Hainan Province Clinical Medical Center (0202068)
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Text and Data Mining valid from 2024-10-17

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Article History

Received: 1 February 2024

Accepted: 1 October 2024

First Online: 17 October 2024

Declarations

:

: The animal experiments were approved by Ethics Committee of the Central South University Xiangya School of Medicine Affiliated Haikou Hospital (No. 2023-LL-389).

: Not applicable.

: The authors declare no competing interests.

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