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Article History

Received: 18 February 2025

Accepted: 27 March 2025

First Online: 15 April 2025

Declarations

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: Ethical approval of this study ([2024] -E-116-R) was obtained from the Ethical Committee of Beijing Children’s Hospital, Capital Medical University. The Institutional Review Board has approved the study protocol involving child participants, and the clinical investigation was conducted according to the principles expressed in the Declaration of Helsinki. In our study, all parents of children who received ACEIs treatment provided written informed consent prior to the initiation of therapy. In clinical practice, physicians thoroughly explained to the parents the rationale for using ACEIs, including potential risks such as hypotension and hyperkalemia, as well as possible benefits like slowing the progression of renal dysfunction and reducing proteinuria, ensuring that parents made an informed decision after comprehensive understanding.

: The authors declare no competing interests.