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NDC80 promotes epithelial to mesenchymal transition of esophageal squamous cell carcinoma through macrophages polarization and PI3K/AKT pathway activation

Crossref DOI link: https://doi.org/10.1186/s40001-025-03397-3

Published Online: 2025-11-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Shu, Jiao

Yang, Chenbo

Sun, Zexin

Liang, Yinghao

Zhao, Na

Liu, Xiaonan

Li, Yiwei

Tabish, Muhammad Saud

Sun, Miaomiao

Chen, Kuisheng
Funding

Funding for this research was provided by:

Training Program for Young and Middle-aged Health Science and TechnologyInnovation Leaders in Henan Province (YXKC2022015)

2024 Key Scientific Research Programfor Higher Education Institutions in Henan Province (24A310023)

National Natural Science Foundation of China (82070222)
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Text and Data Mining valid from 2025-11-10

Version of Record valid from 2025-11-10
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Article History

Received: 15 May 2025

Accepted: 22 October 2025

First Online: 10 November 2025

Declarations

:

: The study was approved by the Ethics Committee of the First Affiliated Hospital of Zhengzhou University (2024-KY-0252–002). Animal experiments were conducted at the Experimental Animal Center of Zhengzhou University, with ethical approval number ZZU-LAC20240322[04].

: The authors declare no competing interests.

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