Zhou, Pan
Li, Xin
Deng, Zhe
Funding for this research was provided by:
Shenzhen Science and Technology Program (KCXFZ2023073109410002)
National Natural Science Foundation of China (No. 82471574)
Shenzhen Clinical Research Center for Trauma treatment (LCYSSQ20220823091405012)
Shenzhen Second People’s Hospital Clinical Research Fund of Shenzhen High-level Hospital Construction Project (No. 20253357007)
Article History
Received: 6 December 2025
Accepted: 16 February 2026
First Online: 26 February 2026
Declarations
:
: This study utilized de-identified data from the eICU Collaborative Research Database (eICU-CRD v2.0). The original data collection was approved by institutional review boards and complied with the Declaration of Helsinki. As this involved secondary analysis of de-identified data, institutional review board approval and individual patient consent were waived in accordance with 45 CFR 46.104(d)(4). Database access was obtained through PhysioNet ( ) following completion of required training and signing of a Data Use Agreement.
: Not applicable. This manuscript does not contain any individual person’s identifiable data.
: The authors declare no competing interests.