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Authors
Xueyou, Lai
Zhenhui, Huang
Desheng, Jia
Zenan, Li
Xin, Wang
Yongchao, Chen
Hongguang, Pan
Nan, Zeng
Shang, Yan
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Funding
Funding for this research was provided by:
the Shenzhen Municipal Science and Technology Innovation Committee (JCYJ20230807093701003)
the Nanshan District Health System Major Science and Technology Project (NSZD2025012)
the Guangdong Medical Research Foundation (A2025293)
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Article History
Received: 4 October 2025
Accepted: 16 February 2026
First Online: 25 February 2026
Declarations
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: This study involving human participants was conducted in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of Shenzhen Children’s Hospital on 4 March 2021 (Protocol No. 2021028). Written informed consent was obtained from the parents and/or legal guardians of all the child participants. Ovine nasal septal tissues were obtained as post‑slaughter byproducts from a licensed abattoir (License No. 503001863) compliant with the Chinese Animal Welfare Act (State Council Decree No. 676), with no animals slaughtered specifically for this research. The study protocol was reviewed and approved (with full ethical review waived) by the Shenzhen Nanshan Hospital Institutional Animal Care and Use Committee (IACUC) on August 1, 2024 (Approval No. YS-24088). Tissue processing adhered to the ARRIVE guidelines and the Chinese national standard for laboratory animal welfare (GB/T 35892-2018).
: The authors declare no competing interests.
