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Authors
Liu, Shuai
Wang, Yu-Bin
Liu, Li-Li
Fang, Shao-Jun
Zhang, Wei-Wei
Liu, Jin-Qian
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Funding
Funding for this research was provided by:
Construction of Provincial-Level Key Clinical Disciplines in Shandong Province (SLCZDZK-2001)
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Article History
Received: 12 December 2025
Accepted: 29 May 2026
First Online: 8 June 2026
Declarations
Ethics approval and consent to participate: This study was conducted in accordance with the Declaration of Helsinki and approved by the Medical Ethics Committee of Binzhou Medical University Hospital (Approval No.: KYLL-333). Written informed consent was obtained from all patients and their family members prior to participation.
Consent for publication: Not applicable.
Competing interests: The authors declare no competing interests.
Clinical trial number: ChiCTR2500107265. The study adheres to CONSORT guidelines. The trial was registered retrospectively (August 7, 2025) after patient enrollment had begun (October 2024). The study protocol was prospectively approved by the Institutional Ethics Committee (KYLL-333) before any patient was enrolled. The study adheres to CONSORT guidelines.
