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Inhibition of EYA family tyrosine phosphatase activity reveals a therapeutic vulnerability and enhances Menin and DOT1L inhibitor efficacy in KMT2A-rearranged leukemia

Crossref DOI link: https://doi.org/10.1186/s40164-025-00717-5

Published Online: 2025-10-22

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Badmus, Lola

Achille, Nicholas J

Zhang, Shubin

Ding, Xianzhong

Zeleznik-Le, Nancy J.
Funding

Funding for this research was provided by:

National Institutes of Health (R01CA233749)
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Text and Data Mining valid from 2025-10-22

Version of Record valid from 2025-10-22
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Article History

Received: 5 May 2025

Accepted: 8 October 2025

First Online: 22 October 2025

Declarations

:

: The authors declare no competing interests.

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