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Authors
Koenen, Mischa H.
de Jonge, Marien I.
Hermsen, Meyke
van Weelden, Geert H.
Olde Olthof, Sanne
van der Gaast-de Jongh, Christa E.
van Opzeeland, Fred
de Kluijs-Bender, Charlene
van Selm, Saskia
van der Vries, Erhard
Bogaert, Debby
Boes, Marianne
de Zoete, Marcel R.
Verhagen, Lilly M.
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Funding
Funding for this research was provided by:
Wilhelmina Children’s Hospital Research Fund
Fellowship clinical research talent from the UMC Utrecht
Nutricia Early Life Nutrition Research grant
Christine Bader Stichting Irene KinderZiekenhuis
Hypatia Fellowship funded by the Radboud University Medical Center
ZonMW VENI grant (09150162010077)
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Article History
Received: 11 September 2025
Accepted: 13 February 2026
First Online: 14 May 2026
Declarations
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: Ethical approval for the DIMER study, part of the National PID study, was received from the Medical Ethical Committee of the Erasmus MC in Rotterdam, the Netherlands (METC:NL40331.078). Legal guardians of all participants signed informed consent, and the study was carried out in accordance with the Declaration of Helsinki. All mice experiments were approved by the Animal Ethics Committee of the Radboud University Nijmegen (RU-DEC: Etiology of the intestinal microbiome in IgA deficiency: AVD 1030020185284).
: Not applicable.
: The authors declare no competing interests.
