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Article History

Received: 27 January 2026

Accepted: 10 September 2026

First Online: 9 October 2026

Declarations

Ethics approval and consent to participate: This study was performed in accordance to the principles of the Declaration of Helsinki with the appropriate approval of the Ethical and Scientific Committees of the Hospital Universitario Central de Asturias and the Regional Ethics Committee from the Principality of Asturias (CEImPA) (approval number: 70/16, date: 5 May 2016 for the project PI16/00280; approval number: 141/19, date: 14 May 2019 for the project PI19/00560). Signed informed consent was obtained from all participants prior to saliva sample collection.

Consent for publication: All participants consented independently when donating samples. All data obtained and generated during the study were kept confidential.

Competing interests: The authors declare no competing interests.