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Epigenetic repression of de novo cysteine synthetases induces intra-cellular accumulation of cysteine in hepatocarcinoma by up-regulating the cystine uptake transporter xCT

Crossref DOI link: https://doi.org/10.1186/s40170-024-00352-4

Published Online: 2024-08-07

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yamauchi, Tomoaki

Okano, Yumi

Terada, Daishu

Yasukochi, Sai

Tsuruta, Akito

Tsurudome, Yuya

Ushijima, Kentaro

Matsunaga, Naoya

Koyanagi, Satoru

Ohdo, Shigehiro
Funding

Funding for this research was provided by:

Japan Society for the Promotion of Science (22KJ2383, 22K18375, 22H00442)

Japan Agency for Medical Research and Development (JP24am121031)
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Text and Data Mining valid from 2024-08-07

Version of Record valid from 2024-08-07
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Article History

Received: 21 March 2024

Accepted: 30 July 2024

First Online: 7 August 2024

Declarations

:

: All authors read and approved the final manuscript.

: The authors declare no competing interests.

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