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Article History

Received: 4 March 2020

Accepted: 2 December 2020

First Online: 6 January 2021

Ethics approval and consent to participate

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The research was approved by the Clinical Research Ethics Committee (<i>Comité de Ética de la Investigación con Medicamentos</i>). The committee’s reference number of the study is PI-2553. This investigation was developed according to the principles of the Declaration of Helsinki and its subsequent amendments. All participants signed informed consent. They were allowed to withdraw the informed consent at any point during the process. All participants followed the protocol used in severe asthma clinics.

: Not applicable.

: The authors declare that they have no competing interests.