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Article History

Received: 31 March 2021

Accepted: 15 September 2021

First Online: 25 September 2021

Declarations

:

: The animal studies were conducted according to the guidance of the National Institutes of Health’s Guide for the Care and Use of Laboratory Animals (NRC, 2011) and approved by the Campus Research and Ethics Committee of the University of the West Indies for animal experimentation (No. CREC-SA.0072/11/2019).The plant was collected with the permission of the Forestry Division of the Ministry of Agriculture, Land and Fisheries, Trinidad and Tobago, and identified at the National Herbarium of Trinidad and Tobago, Department of Life Sciences, University of the West Indies, St. Augustine, Trinidad, and Tobago, and voucher specimen (No. TRIN 50,648) was preserved. The dosages for the plant extract were calculated based on the OECD Guideline 423 for Acute Toxicity Study and based on these results, the 28-day Sub Acute toxicity study dosages were calculated.The ARRIVE guidelines [CitationRef removed] were used for reporting the study and the checklist is added as additional file InternalRef removed.

: All authors consent to the publication of this manuscript.

: All authors declare that they have no competing of interest.