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miR-448 targets IDO1 and regulates CD8+ T cell response in human colon cancer

Crossref DOI link: https://doi.org/10.1186/s40425-019-0691-0

Published Online: 2019-08-07

Published Print: 2019-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lou, Qiong

Liu, Ruixian

Yang, Xiangling

Li, Weiqian

Huang, Lanlan

Wei, Lili

Tan, Huiliu

Xiang, Nanlin

Chan, Kawo

Chen, Junxiong

Liu, Huanliang
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81672413, 81772573)

Guangdong Provincial Department of Science and Technology (2014B020212016, 2017A050501055)

Guangzhou science and technology program (2016201604030007)

Guangzhou science and technology program (2016201604030003)

Overseas Excellent Professor Project

Ministry of Education of China

National Key Clinical Discipline
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Article History

Received: 4 December 2018

Accepted: 24 July 2019

First Online: 7 August 2019

Ethics approval and consent to participate

: All animal experimental procedures were approved and overseen by Animal Ethical and Welfare Committee of Sun Yat-sen University (IACUC DD-17-1101) and were performed in accordance with the guidelines and regulations for animal experiments set down by Sun Yat-sen University. Peripheral venous blood samples from healthy adult volunteers were collected at The Sixth Affiliated Hospital of Sun Yat-sen University. The blood samples were collected after obtaining the patients’ informed consent according to the local ethical committee.

: Not applicable.

: The authors declare that they have no competing interests.