Document is current

Article History

Received: 28 March 2018

Accepted: 25 April 2018

First Online: 10 May 2018

Ethics approval and consent to participate

: All applicable international, national and/or institutional guidelines for the care and use of animals were followed. All animal experiments were approved by the local authorities (Regierungspräsidium Giessen, Germany V54–19 c 20 15 h 01 MR 20/15 Nr. 66/2015).

: The authors declare no competing financial interests. JBK and JMB have equity stakes in, and have received consultancy fees from, Atuka Inc., outside of the submitted work. WHO received personal fees for educational talks and/or consultancy, outside of the submitted work, from Abbvie, Adamas, Bristol-Myer-Squibb, Desitin, Mundipharma, Neuropore, Novartis, Roche and UCB Pharma and grants from the Deutsche Forschungsgemeinschaft, the International Parkinson-Fonds The Netherlands, the Michael J. Fox Foundation, USA, the National Research Fond Luxembourg and from Novartis Pharma, Germany.

: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.