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Article History

Received: 8 March 2021

Accepted: 8 March 2021

First Online: 23 March 2021

Declarations

:

: All study protocols were approved by each participating site’s Institutional Review Board, and written informed consent was obtained from all study participants or their surrogates.

: No individual patient-identifying data is presented in this manuscript.

: Dr. Knopman reported serving on a data safety monitoring board for the DIAN study, serving as an investigator in clinical trials sponsored by Biogen, Lilly Pharmaceuticals, and the University of Southern California, and receiving research support from the National Institutes of Health (NIH) outside of the submitted work. Dr. Graff-Radford reported receiving research support from the National Institute on Aging outside the submitted work. Dr. Lowe reported receiving consulting fees from Bayer Schering Pharma, Piramal Life Sciences, and Merck Research and grants from GE Healthcare, Siemens Molecular Imaging, AVID Radiopharmaceuticals, and the NIH outside the submitted work. Dr. Mielke reported receiving research support from the NIH, Department of Defense, and unrestricted research grants from Biogen outside the submitted work. Dr. Jack reported consulting for Eli Lilly, serving on an independent data monitoring board for Roche, and serving as a speaker for Eisai but receives no personal compensation from any commercial entity; he also reported receiving research support from the NIH and the Alexander Family Alzheimer's Disease Research Professorship of the Mayo Clinic. Dr. Petersen reported receiving consulting fees from Hoffman-La Roche Inc, Merck Inc, Genentech Inc, Biogen Inc, GE Healthcare, and Eisai Inc. outside the submitted work. Dr. Vemuri reported receiving grants from the NIH during the conduct of the study. No other disclosures were reported.