Crossmark

Protein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice

Crossref DOI link: https://doi.org/10.1186/s40478-021-01231-5

Published Online: 2021-07-27

Published Print: 2021-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jeong, Angela

Cheng, Shaowu

Zhong, Rui

Bennett, David A.

Bergö, Martin O.

Li, Ling https://orcid.org/0000-0002-9245-7387
Funding

Funding for this research was provided by:

National Institute on Aging (R01AG031846; RF1AG056976; RF1AG058081, P30AG10161; R01AG15819)
License Information

Text and Data Mining valid from 2021-07-27

Version of Record valid from 2021-07-27
More Information

Article History

Received: 25 May 2021

Accepted: 16 July 2021

First Online: 27 July 2021

Declarations

:

: The Religious Orders Study was approved by an Institutional Review Board of Rush University Medical Center, and all participants signed informed consent, an Anatomic Gift Act, and a repository consent to allow their tissue and data to be shared. All animal procedures used for this study were prospectively reviewed and approved by the Institutional Animal Care and Use Committee of the University of Minnesota (IACUC protocol # 1908-37310A).

: Not applicable.

: The authors declare that they have no competing interests.

Document is current

Any future updates will be listed below