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Developmental deficits and staging of dynamics of age associated Alzheimer’s disease neurodegeneration and neuronal loss in subjects with Down syndrome

Crossref DOI link: https://doi.org/10.1186/s40478-021-01300-9

Published Online: 2022-01-04

Published Print: 2022-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wegiel, Jerzy https://orcid.org/0000-0002-3685-0694
Flory, Michael

Kuchna, Izabela

Nowicki, Krzysztof

Wegiel, Jarek

Ma, Shuang Yong

Zhong, Nanbert

Bobrowicz, Teresa Wierzba

de Leon, Mony

Lai, Florence

Silverman, Wayne P.

Wisniewski, Thomas
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Article History

Received: 14 October 2021

Accepted: 2 December 2021

First Online: 4 January 2022

Declarations

:

: All procedures involving human tissues were performed in accordance with the World Medical Association Declaration of Helsinki. Experimental protocols were approved by IBR’s Institutional Review Board. The study was performed by using coded and anonymized brain tissue samples obtained from the tissue banks listed in the Acknowledgements. The anonymized extracts of clinical records were obtained from the New York State Brain and Tissue Bank for Developmental Disabilities and Aging at the New York State Institute for Basic Research in Developmental Disabilities.

: Not applicable.

: The authors declare that they have no competing interests.

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