Zhao, Beibei
Cowan, Catherine M.
Coutts, Juliane A.
Christy, Darren D.
Saraph, Ananya
Hsueh, Shawn C. C.
Plotkin, Stephen S.
Mackenzie, Ian R.
Kaplan, Johanne M.
Cashman, Neil R. https://orcid.org/0000-0002-0080-1006
Funding for this research was provided by:
ProMIS Neurosciences (SRA F16-05805)
Canadian Institute of Health Research (PJT-159546)
Canadian Institute of Health Research (CCNA-20R04367)
Fondation Brain Canada (20R74974, F20-04056)
William A. Lambert donation (F17-00928)
Article History
Received: 9 October 2023
Accepted: 6 December 2023
First Online: 18 December 2023
Declarations
:
: All of the human post-mortem materials used in this study were obtained from subjects who had been evaluated at the Sunnybrook Health Sciences Centre ALS Clinic and the University of British Columbia Clinic for Alzheimer’s Disease and Related Disorders, and consented for research purposes in accordance with respective ethical review boards.
: Not applicable.
: N.R.C., J.M.K., and B.Z. are current employees of ProMIS Neurosciences. S.S.P. and S.C.C.H. have received consultation compensation from ProMIS Neurosciences. S.S.P. and B.Z. possess ProMIS stock options. N.R.C. and J.M.K. possess ProMIS shares and stock options. S.S.P. is the inventor on patent applications for Collective Coordinates computational modeling. N.R.C., S.S.P., J.M.K., and B.Z. are inventors on patent applications relating to conformation-specific epitopes in RACK1, antibodies thereto and methods related thereof.