Zelina, Pavol
de Ruiter, Anna Aster
Kolsteeg, Christy
van Ginneken, Ilona
Vos, Harmjan R.
Supiot, Laura F.
Burgering, Boudewijn M. T.
Meye, Frank J.
Veldink, Jan H.
van den Berg, Leonard H.
Pasterkamp, R. Jeroen http://orcid.org/0000-0003-1631-6440
Funding for this research was provided by:
Stichting ALS Nederland (TOTALS, GoALS)
E-Rare (MAXOMOD)
JPND (TRIAGE)
ALS Cure project
Nederlandse Organisatie voor Wetenschappelijk Onderzoek (X-omics initiative)
H2020 European Research Council (EScORIAL)
Article History
Received: 11 July 2024
Accepted: 15 August 2024
First Online: 4 September 2024
Declarations
:
: All subjects have provided written informed consent and generation of iPSC lines was approved by the Ethical Medical Committee of the University Medical Center Utrecht. Patients were diagnosed according to the diagnostic criteria for ALS (revised El Escorial). Controls were donors without a psychiatric or neurologic diagnosis (Supplementary material : Supplementary Table S6).
: Not applicable.
: J.H.V. reports to have sponsored research agreements with Biogen and Astra Zeneca. R.J.P. reports to have sponsored research agreements with Amylyx. The other authors declare no competing interests.