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Authors
Jimenez Garcia, Leyre
Ryan, Lindsay N.
Gross, Amy C.
Albrecht, Annika M.
Walters, Jefferson H.
Leonard, Jeffrey R.
Roberts, Ryan D.
Reinecke, James B.
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Funding
Funding for this research was provided by:
Pelotonia (Scholar)
Alex's Lemonade Stand Foundation for Childhood Cancer (Crazy 8)
Alex's Lemonade Stand Foundation for Childhood Cancer (Young Investigator Award)
National Cancer Institute (R01CA260178)
National Center for Advancing Translational Sciences (UL1TR002733)
Nationwide Children's Hospital
CancerFree KIDS (Wolf Pack Research Grant)
St. Baldrick's Foundation (Scholar Award)
Hyundai Hope On Wheels (Bridge2K)
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Article History
Received: 5 November 2025
Accepted: 5 February 2026
First Online: 1 April 2026
Declarations
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: This study used pre-established and patient-derived human cell lines that are commercially available (Brain Tumor Resource Lab, ATCC, Sigma-Aldrich and ScienCell). According to institutional and national guidelines, research involving such cell lines does not require ethics committee approval because the material is anonymized and information identifying the donor is not accessible. Animal care and experiments were approved by the Institutional Animal Care and Use Committee of the Abigail Wexner Research Institute at Nationwide Children’s Hospital (IACUC protocol #AR15-00022).
: De-identified MR images were obtained after approval from Nationwide Children’s Hospital Institutional Review Board. Consent was not deemed to be necessary.
: All other authors declare no competing interests.
