Yang, Tao
Ay, Yeonglong
Kaur, Sukhneet
Butler, Robert R. III
Tran, Kevin C.
Liu, Harry
Langness, Vanessa F.
Massa, Stephen M.
Longo, Frank M.
Funding for this research was provided by:
Resources at the San Francisco VA Health Care System.
Scully Initiative
Taube Philanthropies
Jean Perkins Foundation
Article History
Received: 15 September 2025
Accepted: 16 February 2026
First Online: 5 March 2026
Declarations
:
: All animal procedures were conducted in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals using protocols approved by the Institutional Animal Care and Use Committee at Stanford University.
: Not applicable.
: Drs. Longo and Massa are listed as inventors on patents relating to p75NTR modulation, which are assigned to UNC, UCSF, and the VA. Drs. Longo and Massa are eligible for royalties distributed by the assigned universities. Dr. Longo has financial interest in PharmatrophiX, a company focused on the development of small-molecule ligands for neurotrophin receptors, which has licensed several of these patents.