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Article History

Received: 19 December 2025

Accepted: 21 March 2026

First Online: 21 April 2026

Declarations

:

: All patients gave written informed consent in accordance with the Declaration of Helsinki in its currently form. All procedures were approved by the official institutional ethics review committee (EA1/144/21) at the Charité - University Hospital Berlin. This manuscript follows the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines for reporting observational studies.

: Not applicable.

: S. Hoffmann, K. Brokamp, A. Meisel, P. Doksani, L. Helmig, J.C. Rückert, M. Pumberger, F. Schömig, M. Wolfsgruber, I. Koneczny, M. Mayrhofer, M. Blüthner, Ruck, M. Pawlitzki, W. Stenzel, C. Preusse declare no conflict of interest related to this paper, M. Schuelke received funding from the DFGOther (e.g. grants, consulting fee, honoraria, as well as leadership roles): S. Hoffmann: argenx, Janssen, Alexion Pharmaceuticals, Kyverna, Novartis, Roche, Grifols, Member of the Medical Advisory Board of the German Myasthenia Society (DMG); A. Meisel: Alexion (AstraZeneca Rare Disease), argenx, Axunio Pharma GmbH, Octapharma, UCB, Deutsche Forschungsgemeinschaft, Leducq Foundation, Einstein Foundation Berlin, Janssen Pharmaceuticals, Merck, Xcenda, Boehringer, Desitin, Dierks, Grifols, Hormosan, Pfizer/BMS, Deutsche Myasthenie Gesellschaft (DMG), Bundesinstitut für Qualität und Patientensicherheit (BQS)/ DMG, Berliner Schlaganfall-Allianz; P. Doksani: UCB Pharma, Alexion; M. Schuelke: UCB, Medizinische Marktforschung Berlin, Atheneum, DGM, Khondrion; T. Ruck: argenx, Alexion, Merck, Roche, UCB, Member of the Medical Advisory Board of the German Myasthenia Society (DMG); M. Pawlitzki: Argenx, Alexion, Bayer Health Care, Biogen, Demecan, Hexal AG, Janssen Cilag, Merck Serono, Neuraxpharm, Novartis, Roche, Sanofi-Aventis, Teva, Viatris, Takeda, Amicus Therapeutics; W. Stenzel: Alexion, GSK, Member of the programme committee and the executive board of the World Muscle Society; C. Preusse: DGM, DFG, Myositis-Netz e.V., Alexion, argenx, WMS, Supporting scientific committee ICN conference.