Waldron, Fergal M. https://orcid.org/0000-0003-2622-0776
Spence, Holly
Taso, Orjona Stella
Read, Fiona L.
Sinha, Irika R.
Irwin, Katherine E.
Wong, Philip C.
Ling, Jonathan P.
Gregory, Jenna M. https://orcid.org/0000-0003-3337-4079
Funding for this research was provided by:
NHS Grampian
National Institute of Neurological Disorders and Stroke
U.S. Food and Drug Administration
LifeArc
Target ALS
Article History
Received: 31 May 2026
Accepted: 10 September 2026
First Online: 9 October 2026
Declarations
Ethics approval and consent to participate: All post-mortem tissue was collected via the Edinburgh Brain Bank (ethics approval from East of Scotland Research Ethics Service, (REC: 21/ES/0087, IRAS: 298880)) in line with the Human Tissue (Scotland) Act. Use of human tissue for post-mortem studies has been reviewed and approved by the Edinburgh Brain Bank ethics committee and the Academic and Clinical Central Office for Research and Development (ACCORD) medical research ethics committee (AMREC). Not applicable.
Consent for publication: Not applicable.
Competing interests: The authors declare no competing interests.