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Article History

Received: 14 May 2025

Accepted: 17 September 2025

First Online: 15 October 2025

Declarations

:

: This study has been approved by the Ethics Committee of Nanjing Stomatological Hospital , Affiliated Hospital of Medical School, Institute of Stomatology, Nanjing University (Approval Number: NJSH-2023NL-036), and followed the contents in the Declaration of Helsinki concerning human subjects.

: The undersigned author(s) of the manuscript titled “A novel machine-learning-based model for prediction of open gingival embrasures between mandibular central incisors after clear aligners treatment: A retrospective cohort study” hereby grant “Progress in Orthodontics” the right to publish the aforementioned work, including any supplementary material that may be associated with it. We confirm that this work is original, has not been published elsewhere, and does not infringe upon any copyright or any other rights of any third party. We also affirm that all contributing authors have agreed to the submission of this work for publication in “Progress in Orthodontics.” In the event that this work includes any data or images from individuals, we confirm that we have obtained the necessary consents from the individuals involved.

: The authors declare no competing interests.